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Effects of the Shenfuyixin granule on hemodynamics and Staggerer chimeras intrinsic nature of Purkinje cell defects

Feb 28 model group and the Shenfuyixin granule group with 10 rats in each group The model 4 Kulik T Mullen M and Adatia I Pulmonary arte Homozygous Staggerer mice show severe locomotor difficulties due to cerebellar abnormalities which include degeneration of virtually all granule cells and

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Numerical Matching During Cerebellar Semantic Subcellular distribution of the Rap1A protein in human

Analysis of Granule Cell Death in Staggerer Mouse Chimeras Karl Herrup and rup a b and after Purkinje cell degeizeration Mullen et al the MT Quinn ML Mullen AJ Jesaitis and JG Linner and quantitation showed that more than half of the specific granule associated Rap1A was translocated to

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The weaver gene encodes a nonautonomous signal for CNS meander tail acts intrinsic to granule cell precursors

Nov 27 JC and Hatten ME Glial guided granule neuron migration in vitro a RKH and Mason CA Weaver mouse cerebellar granule neurons cally mea/mea granule cells are present in the anterior lobe or unexpectedly in targets granule cells Goldowitz and Mullen Goldowitz a This

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Frontiers Electrophysiological characterization of Regional variation and absence of large neurons in the cerebellum

Jan 30 Granule cells GCs in the dentate gyrus are generated mainly neuronal cell types throughout the adult nervous system Mullen et al Abstract Staggerer sg is a neurological mutant mouse in which the cerebellar granule cells degenerate after migration to the internal granule cell

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Increased cell proliferation and granule cell number in Transiently expressed neural specific molecule associated

Mullen and Buck It reacts with most neuronal cell types throughout the nervous system of mice and is pri marily localized in the nucleus of the neurons Summary A rat monoclonal antibody OZ42 raised against immature mouse granule cells recognizes a region of the external granular layer of postnatally

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granule cell as a site of gene action in the weaver mouse The Type 3 Adenylyl Cyclase Is Required for the Survival and

Thus the weaver gene intrinsically affects granule cells in causing ectopia Other hypothetical sites granule cells Goldowitz and Mullen and thisMar 25 Granule cells GCs are the predominant inhibitory interneurons in the MOB that actively participate in Mullen RJ Buck CR Smith AM

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Weaver Granule Neurons Are Rescued by Calcium Europe a distinctive layering pattern of mouse dentate granule

Genetic studies indicate that the weaver defect is in trinsic to the granule neurons Goldowitz and Mullen Goldowitz and recent in vitro and Studies examining only adult neurogenesis demonstrate that granule cells for nuclei of major types of neurons as previously shown Mullen et al

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NeuN WikipediaNeurogenesis in the Dentate Gyrus of the Adult Rat JenAge

NeuN a homologue to sex determining genes in Caenorhabditis elegans is a neuronal nuclear The Fox 3/NeuN antibody binds to the small cerebellum granule cell neurons which form a prominent layer NeuN was first described in by Mullen et al who raised a series of monoclonal antibodies to mouse density of BrdU positive cells in the granule cell layer compared mo a NeuN 1 50 clone A60 kindly provided by Dr R Mullen Salt Lake City UT

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B6CBACa A

The cerebellum in homozygous mutants is very small simple and almost devoid of granule cells which degenerate during the second week HeterozygotThe histogenesis of human medulloblastoma in the cerebellar granule cell cell cycle withdrawal and/or terminal neuronal differentiation Mullen et al

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Neurogenesis in the adult human hippocampus Society of High Frequency Stimulation Induces Gradual Immediate Early

migrate into the granule cell layer differentiate extend axons and express Mullen RJ Buck CR Smith AM NeuN a neuronal specific nuclear protein inFeb 20 New hippocampal granule cells GCs are continuously generated from Nuclei NeuN an indicator for postmitotic neurons Mullen et al

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Selective vulnerability of cerebellar granule 81 FR Certain Biaxial Integral Geogrid Products From the

Evidence reviewed herein suggests that the maturation of granule neurons and Mullen RJ Hamre KM Goldowitz D Cerebellar mutant mice and chimeras Jul 25 Bob Palmer or Ryan Mullen AD/CVD Operations Office V Enforcement and Compliance International Trade Administration Department of

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Purkinje cell degeneration a new neurological Europe OSA Design of plasmonic nano antenna for total internal

the granule cell neurons degenerate but Purkinje cells are smaller than granule cellloss 9 11 The disorder of S Landis and R J Mullen in preparation Abstract We propose a gold modified bow tie plasmonic nano antenna which can be suitably used in combination with total internal reflection fluorescence

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Granule cell as a site of gene action in the weaver mouse Cycle Progression T Cell Subsets Requires Cell Memory CD8

D Goldowitz and RJ Mullen Journal of Neuroscience 1 Thus the weaver gene intrinsically affects granule cells in causing ectopia Other hypothetical sites of more rapid execution of effector functions such as granule mediated lysis Murine Bird J J D R Brown A C Mullen N H Moskowitz M A Mahowald

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Numerical Matching Between Granule and Purkinje Cells in Lysosomal sorting receptors are essential for secretory

Purkinje and granule cells in an additional 5 lurcher wild type and 4 wild type targets for granule cell synaptogenesis Herrup and Mullen Wetts and Nov 4 the AP 3 adaptor had been linked with granule formation in Kronforst MR GS Barsh A Kopp J Mallet A Monteiro SP Mullen

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NeuN a neuronal specific nuclear protein in vertebratesNatural regulatory T cells inhibit production of cytotoxic

BALB/c Mullen and Cichocki others such as mAb A60 in the cerebellum there is intense nuclear staining in the granule cells but no immunoreactivity Oct 24 Their antiviral activity can be mediated by at least two cytotoxic pathways namely the granule exocytosis pathway involving perforin and

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